Aoshukang ®—— Compound Amoxicillin Breast Injector

【 Main ingredients 】 Amoxicillin trihydrate, sulbactam sodium, and prednisolone.

【 Appearance 】 This product is a white to off white oily suspension.

Pharmacological effects: Amoxicillin is a broad-spectrum β - lactam antibiotic that exerts bactericidal activity by inhibiting bacterial cell wall synthesis. It has bactericidal activity against various Gram positive and negative bacteria that cause mastitis, such as Staphylococcus, Streptococcus, and Escherichia coli. Sulbactam is an irreversible competitive β - lactase inhibitor that can inhibit the damage of β - lactase types II, III, IV, and V to β - lactam antibiotics, thereby enhancing the antibacterial activity of β - lactam antibiotics. Prednisolone has anti-inflammatory effects, helping to reduce inflammation and tissue swelling, and promoting the recovery of mastitis.

Pharmacokinetic studies showed that the concentration of amoxicillin in milk reached its highest point of 352.75 µ g/ml at 3.33 hours after injection of the drug into the milk tube three times in a row; The concentration of prednisolone reached its peak at 26.20 µ g/ml after approximately 2.5 hours; The concentration of sulbactam reached its highest at 134.68 µ g/ml at 2.33 hours. After injection into the milk duct, amoxicillin, prednisolone, and sulbactam are mainly excreted with milk during milking.

【 Function and Application 】 Mainly used to treat mastitis in lactating cows caused by sensitive Gram positive and Gram negative bacteria.

【 Usage and Dosage 】 Milk tube injection: 3g per milk chamber after milking, administered once every 12 hours, for 3 consecutive times.

[Adverse reactions] This product contains amoxicillin, which may cause extremely rare allergic reactions.

【 Precautions 】

(1) This product is only used for cows, and cows after using this product are not edible.

(2) Insufficient research on the residual limit of sulbactam in milk, attention should be paid to the risks of use.

(3) Penicillin allergy sufferers should avoid contact with this product.

(4) Users need to take protective measures to avoid direct contact with this product.

(5) Keep out of reach of children.

[Rest period] Abandoned milk period of 60 hours.

【 Specification 】 3g: 0.2g (calculated as C16H19N3O5S)+0.05g (calculated as C8H11NO5S)+0.01g (calculated as C21H28O5)

【 Storage 】 Store below 25 ℃, sealed (disposable syringe).

【 Packaging 】 3g/piece x 24 pieces/box x 6 boxes/box, 3g/piece x 24 pieces/box x 4 boxes/box